May 4, 1880.

Sunday May 4

An altered pattern of epigenetic modifications is central to many common human diseases, including cancer. Many studies have explored the mosaic patterns of DNA methylation and histone modifications in cancer cells on a gene-by-gene basis, among them the seminal finding of transcriptional silencing of tumor suppressor genes by CpG island promoter hypermethylation. Epigenetic gene inactivation i...

Dmd058347 1873..1880

Historically, since the metabolism of administered peptide/protein drugs (“biotherapeutics”) has been expected to undergo predictable pathways similar to endogenous proteins, comprehensive biotherapeutic metabolism studies have not been widely reported in the literature. However, since biotherapeutics have rapidly evolved into an impressive array of eclectic modalities, there has been a shift t...

Access published May 4 , 2007

Notes in Computer Science 1880

This paper introduces the XTR public key system. XTR is based on a new method to represent elements of a subgroup of a multiplicative group of a finite field. Application of XTR in cryptographic protocols leads to substantial savings both in communication and computational overhead without compromising security.

Arthur Henry Morse 1880 - 1950

Dr. Arthur Henry Morse died on January 26, 1950 at the age of 69. He is survived by his wife and two sons. After graduation from Tufts College in 1902 and the Johns Hopkins Medical School in 1906, he served as resident in pathology at the Rhode Island General Hospital. Subsequently, in 1910, he became resident and instructor in obstetrics at Johns Hopkins Hospital and in 1912 resident surgeon a...